On the other hand, in a limited clinical trial with the δ opioid agonist AZD2327 in anxious, depressed patients, although the drug’s effects overall failed to reach significance, it was concluded that AZD2327 had larger potential anxiolytic than antidepressant activity ( Richards et al., 2016 ).
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A Novel G Protein-Biased Agonist at the <i>δ</i> Opioid Receptor with Analgesic Efficacy in Models of Chronic Pain.
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