Barely Significant
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Evaluation of capsular contracture following immediate prepectoral versus subpectoral direct-to-implant breast reconstruction.

Sci Rep · 2020 · PMC6981172 · PMID 31980737

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a trend toward significanceno p-value reported
Despite high inter-rater reliability, the difference in capsular contracture rate between prepectoral and subpectoral cohorts was unable to achieve significance for each evaluator; however, given the result of the combination group, we anticipate a trend toward significance with a larger sample.

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an increasing trendno p-value reported
There is an increasing trend towards direct-to-implant (DTI) reconstruction in many centers, where the permanent implant is placed at the time of mastectomy in a subpectoral position, with the breast soft tissue supported along the inferolateral pole with a biomaterial surgical mesh, such as acellular dermal matrix (ADM) or synthetic material 5 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.