Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components.

Cell Commun Signal · 2020 · PMC6986015 · PMID 31987044

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Also, with Leu-8ADT and βAsp-8ADT there was an overall trend of a further increase in cell death upon TRADD knockdown, and while Fas knockdown produced a slight increase in cell death in HCT116 cells, Fas was partially required for Leu-8ADT- and βAsp-8ADT-induced cell death in LNCaP cells (Additional file 5 : Figure S16).

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