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From Experiments to Simulation: Shear-Induced Responses of Red Blood Cells to Different Oxygen Saturation Levels.

Front Physiol · 2019 · PMC6987081 · PMID 32038272

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a decreasing trendno p-value reported
Thus, it is likely that the volume of RBCs shows a decreasing trend in deoxygenation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.