Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia.

Additional association analyses of LCN2 and MMSE scores including all groups with cerebrovascular disease (SVDND, VCIND, and VaD) showed highly significant negative correlations in cohort 1 (cc = −0.55, p < 0.0001, Fig. 3c , Spearman correlation test) and cohort 4 (cc = −0.56, p = 0.008, Fig. 3d , Spearman correlation test).

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