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Safety of Ixekizumab Treatment for up to 5 Years in Adult Patients with Moderate-to-Severe Psoriasis: Results from Greater Than 17,000 Patient-Years of Exposure.

Dermatol Ther (Heidelb) · 2020 · PMC6994584 · PMID 31749092

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a decreasing trendno p-value reported
Most AEs were not serious, and the rate of discontinuation due to AEs was low, with a decreasing trend over time.

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