However, when using dedicated brain PET images or particularly dynamic PET images with arterial blood sampling at multiple time points for the absolute quantification of regional metabolic rates, regional differences lower than 10% may be significant.
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Effect of various blood glucose levels on regional FDG uptake in the brain.
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The sentences
In the gross analysis of regional brain FDG uptake using whole-body images, the regional differences of <10% may not be significant.