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miR-221-3p Drives the Shift of M2-Macrophages to a Pro-Inflammatory Function by Suppressing JAK3/STAT3 Activation.

Front Immunol · 2019 · PMC6996464 · PMID 32047494

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a slight trendno p-value reported
TLR3 activation via PolyIC treatment caused a slight trend to downregulate miR-221-3p and miR-27a-3p in M2-macrophages, but did not affect miR-155-5p.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.