Mechanisms of insulin resistance related to white, beige, and brown adipocytes.

Mol Metab · 2020 · PMC6997501 · PMID 32180558

Europe PMC DOI

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highly significantno p-value reported

While there have been highly significant improvements in therapies for type 2 diabetes, it could be argued that there has been no breakthrough with the equivalent impact on the discovery of insulin itself in 1921.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.