PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma.

We also detected slightly lower lysosomal LPC levels in the TBI+AACOCF 3 mice, this however failed to reach significance as compared to TBI+vehicle controls ( Figure 5D ), suggesting potential involvement of additional phospholipases (Table S2 & S3).

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