In this light, our work on addressing the specificity of biosensor binding using NMR structural analysis is likely to be significant.
← all excerpts
A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells.
3
—
—
The sentences
It is striking and highly significant that our biosensor reveals evidence of such signal integration, in single cell imaging experiments in-vitro.
This is an interesting trend suggesting that intracellular regions showing higher Fyn activity is likely to show reduced overall membrane motility changes.