Cyclosporine H Improves the Multi-Vector Lentiviral Transduction of Murine Haematopoietic Progenitors and Stem Cells.

CsH led to a highly significant increase in the expression of each of these reporters (Figs. 2A–D and 3A–D ) and, more importantly, increased the percentage of cells expressing all three fluorescent proteins simultaneously from less than 1% to an average of 2–3% in both cell populations (from an average of 0.85% to an average of 2.95% in GMPs and from an average of 0.33% to an average of 1.98% in HSCs, Figs. 2E and 3E ).

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