Barely Significant
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Using referral rates for genetic testing to determine the incidence of a rare disease: The minimal incidence of congenital hyperinsulinism in the UK is 1 in 28,389.

PLoS One · 2020 · PMC7004321 · PMID 32027664

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an overall trendno p-value reported
We did not detect an overall trend of increasing incidence from 2007–2016 ( S2 Table ), however the increase in numbers may well have occurred prior to this time period.

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