Barely Significant
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Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD).

PLoS One · 2020 · PMC7004328 · PMID 32027677

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a decreasing trendno p-value reported
There was a decreasing trend in the concentration of all CE species in subjects with COPD ( S2 Table ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.