Barely Significant
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Clinical efficacy and safety of anti-PD-1/PD-L1 inhibitors for the treatment of advanced or metastatic cancer: a systematic review and meta-analysis.

Sci Rep · 2020 · PMC7005709 · PMID 32034198

Europe PMCDOI
1
hedged sentence
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

an evident trendP ≤ 0 . 001actually significant
Moreover, there was an evident trend to favour ICIs than control therapies for cancer patients in control group with placebo (OS: HR: 0.64, 95% CI: 0.53–0.77, P ≤ 0 . 001 ; PFS: HR: 0.55, 95% CI: 0.47–0.65; P ≤ 0 . 001 ) and chemotherapy (OS: HR: 0.74, 95% CI: 0.68–0.80, P ≤ 0 . 001 ; PFS: HR: 0.79, 95% CI: 0.69–0.90; P ≤ 0 . 001 ), but not with biologics (OS: HR: 0.93, 95% CI: 0.74–1.16, P = 0 . 496 PFS: HR: 0.97, 95% CI: 0.80–1.17; P = 0 . 730 ).

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