Sex-specific Estrogen Levels and Reference Intervals from Infancy to Late Adulthood Determined by LC-MS/MS.

J Clin Endocrinol Metab · 2020 · PMC7007877 · PMID 31720688

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In conclusion, we present a novel highly sensitive LC-MS/MS for simultaneous quantification of E1 and E2 (and E3) and present reference ranges throughout life with highly significant sex dimorphic changes with age, pubertal stage, menstrual cycle, and menopausal status.

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