Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses.

Cell Rep · 2019 · PMC7010214 · PMID 31851929

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a decreasing trendno p-value reported

This is exemplified by cluster 4, mainly composed of human H3N2 NS1-containing recombinant viruses, which displayed a decreasing trend from day 2 to day 5 post-infection because of their inability to establish robust levels of viral replication in vivo ( Data S2d ).

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