Antiparasitic activity of furanyl N-acylhydrazone derivatives against Trichomonas vaginalis: in vitro and in silico analyses.

Finally, the need for new and effective molecules for treating trichomoniasis is emerging exponentially and all data gathered here show that furanyl N- acylhydrazone derivatives, PFUR 4a and 4b, have a highly significant antiparasitic activity against T. vaginalis with a great level of selectivity for the parasite over non-tumor/normal cells and are, therefore, promising molecules for studies on new trichomonacidal agents.

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