A mouse model of MSU-induced acute inflammation <i>in vivo</i> suggests imiquimod-dependent targeting of <i>Il-1β</i> as relevant therapy for gout patients.

Theranostics · 2020 · PMC7019178 · PMID 32104502

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highly significantno p-value reported

Among the genes exhibiting highly significant transcriptional repression, Il-1β , as well as inflammasome components (e.g Nlrp3 ) appeared of particular importance (Supplementary Fig.

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