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<i>Helicobacter pylori</i> Eradication According to Sequencing-Based 23S Ribosomal RNA Point Mutation Associated with Clarithromycin Resistance.

J Clin Med · 2019 · PMC7019680 · PMID 31881688

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a decreasing trendno p-value reported
Resistance to metronidazole has increased worldwide; however, in Korea, a decreasing trend in metronidazole resistance was observed in several studies [ 10 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.