On the relationship of first-episode psychosis to the amphetamine-sensitized state: a dopamine D<sub>2/3</sub> receptor agonist radioligand study.

Although the interpretation of this finding is not straightforward, the finding was highly significant and is somewhat supported another [ 11 C]-(+)-PHNO study 50 that found a negative relationship between stress-induced DA release in SNVTA and negative symptoms in individuals with clinical high risk for schizophrenia (and at trend level, also patients with FEP).

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