High-fat diet-induced dysbiosis mediates MCP-1/CCR2 axis-dependent M2 macrophage polarization and promotes intestinal adenoma-adenocarcinoma sequence.

J Cell Mol Med · 2020 · PMC7028862 · PMID 31957197

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a decreasing trendno p-value reported

Immunofluorescent indicated that the number of total macrophages (F4/80) and M2 TAMs (MR) in HFD group were significantly higher than those in control group, whereas M1 TAMs (iNOS) of HFD mice presented a decreasing trend (Figure 5 A‐B).

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