Although the ratio of CD4 + IFN-γ + T (T helper 1, Th1) cells showed an increasing trend in AD+IIV mice, the ratio did not significantly differ from that in AD mice (Fig. 5 b).
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Influenza vaccination in early Alzheimer's disease rescues amyloidosis and ameliorates cognitive deficits in APP/PS1 mice by inhibiting regulatory T cells.
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