P < 0.05 were considered statistically significant (*), P < 0.01 were considered highly significant ( ⁎⁎ ) and P < 0.001 were considered extremely significant ( ⁎⁎⁎ ), respectively. 3 Results and discussion 3.1 Synthesis and characterization of B-TPP As depicted in Scheme 1 , carbodiimide chemistry was used to covalently conjugate TPP to Brij 98.
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Triphenylphosphonium-modified mitochondria-targeted paclitaxel nanocrystals for overcoming multidrug resistance.
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