Evidence Implicating Non-Dioxin-Like Congeners as the Key Mediators of Polychlorinated Biphenyl (PCB) Developmental Neurotoxicity.

The authors reported that while there were no significant associations for total PCBs and ASD, there were marginally significant associations linking DL-PCB exposure and reduced risk for diagnosis of non-typical development (adjusted OR: 0.41 (95% CI 0.15 to 1.14)) and between RyR-active NDL PCBs and increased risk for ASD diagnosis (adjusted OR: 2.63 (95% CI 0.87 to 7.97)).

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