In-silico Analysis of <i>NF1</i> Missense Variants in ClinVar: Translating Variant Predictions into Variant Interpretation and Classification.

The non-parametric one way ANOVA of prediction scores distribution among categories was highly significant for all three metapredictors ( p < 0.0001 for all predictors with VEST3 Kruskal-Wallis statistic K = 156.1, REVEL Kruskal-Wallis statistic K = 113, ClinPred Kruskal-Wallis statistic K = 168).

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