Note, however, that even though the associations for HLA-B and HLA-C were highly significant, the actual effect of heterozygosity on viral load was quite small (effect size = −0.25 and –0.21, respectively).
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HLA Heterozygote Advantage against HIV-1 Is Driven by Quantitative and Qualitative Differences in HLA Allele-Specific Peptide Presentation.
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