Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD.

Mol Neurodegener · 2020 · PMC7041170 · PMID 32093728

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4 a), whereas an analysis of the nucleoplasm revealed a highly significant increase in both the number of NPM1 molecules/cluster and cluster area, indicating disassembly of the nucleolus and translocation of NPM1 from the nucleolus to nucleoplasm (Fig. 4 b,c).

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