These results are particularly surprising since the difference in the plasma S-Klotho levels of the middle-aged and young men and women only showed a trend towards significance; this might have a physiological (e.g., the better health status of young individuals) or methodological explanation (e.g., the blood samples of the FIT-AGEING and ACTIBATE projects were analysed at different times of the year).
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Relationship between plasma S-Klotho and cardiometabolic risk in sedentary adults.
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