In a review, the ratio of glottic to supraglottic tumors was 2.12:1 in men and 0.56:1 in women, which remains highly significant. 5 In a multicenter study comprising 4005 patients with head and neck cancer, women with laryngeal cancer had a reduced risk for recurrence compared with men (HR = 0.39, 95% CI: 0.24‐0.74). 6 In a series of 1252 consecutive patients with LSCC who all were treated with primary radiotherapy, multivariate analyses revealed that male gender was a significant factor in predicting locoregional failure, death from cancer, and death from all causes. 7 2.3.
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