Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer.

Cancer Immunol Immunother · 2020 · PMC7044156 · PMID 31893287

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

at the margin of statistical significanceP = 0.053so close (0.05 < p ≤ 0.1)

2 ), the small group of patients who died during the follow-up period ( N = 7) had a neoadjuvant HMGB1 profile pattern mirroring that of a positive DMFS event, with decline during NACT before reverting during CRT, both alterations at the margin of statistical significance ( P = 0.053 and P = 0.049, respectively).

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