Does chronic hyperglycaemia increase the risk of kidney stone disease? results from a systematic review and meta-analysis.

Heterogeneity and sensitivity analysis There was borderline significant statistical heterogeneity between DM cohort studies in unadjusted risk (Tau 2 =0.042, Cochran’s Q=9.50, p=0.05, I 2 =62.3%), however there was significant heterogeneity when risk was adjusted (Tau 2 =0.070, Cochran’s Q=13.70, p=0.008, I 2 =80.2%).

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The results are highly significant although are limited by heterogeneity, despite meta-regression analysis.

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