Resting Whole Body Energy Metabolism in Class 3 Obesity; from Preserved Insulin Sensitivity to Overt Type 2 Diabetes.

Due to the lower BMI observed in the insulin-sensitive subjects, REE was adjusted for the Kg of free fat mass and the difference between groups remained highly significant (32.2±4.5, 30.3±3.7 and 28.9±3.3 Kcal/kg of free fat mass/day in T2DM, insulin-resistant and insulin-sensitive patients, respectively; P<0.0001) ( Figure 2 left panel).

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