The role of ubiquitination in tumorigenesis and targeted drug discovery.

Signal Transduct Target Ther · 2020 · PMC7048745 · PMID 32296023

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an increasing trendno p-value reported

The cancer-associated AKT mutation displays an increasing trend in AKT ubiquitination. 175 In addition, SKP2 is also the E3 ligase for ErbB-receptor-mediated AKT ubiquitination.

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