Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9.

Mol Ther · 2020 · PMC7054720 · PMID 31981492

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highly significantno p-value reported

46 The magnitude of IOP reduction achieved by Aqp1 disruption in the normal eye is highly significant because reduction may be limited to a minimum pressure in the mouse.

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