a trend toward significanceP = 0.12
High-Mobility Group Box 1 HMGB1 levels in the perfusate increased over the 3-hour perfusion period, demonstrating a trend toward significance (1 h: 0.46 ± 0.5 ng/mL versus 3 h: 9.98 ± 5.5 ng/mL, P = 0.12; Figure 4 ).