Metformin: current clinical applications in nondiabetic patients with cancer.

Aging (Albany NY) · 2020 · PMC7066888 · PMID 32074084

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an overall trendno p-value reported

showed that there is an overall trend towards better outcomes in patients receiving ipilimumab, nivolumab, and/or pembrolizumab plus metformin [ 111 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.