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A Hierarchical Age-Period-Cohort Analysis of Breast Cancer Mortality and Disability Adjusted Life Years (1990-2015) Attributable to Modified Risk Factors among Chinese Women.

Int J Environ Res Public Health · 2020 · PMC7068251 · PMID 32093283

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a decreasing trendno p-value reported
The cohort 1910 to 1935 showed a rising trend of random cohort effects in MRs; additionally, a decreasing trend of random effects was reported in the overall cohort (1910 to 1970), suggesting that the early cohorts were positively associated with MRs due to breast cancer (see Figure S2, Supplementary Materials ).

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an increasing trendno p-value reported
We observed an increasing trend of coefficient in the random effect of age from 50 to 80 years, which suggested that older ages were positively associated with MRs from breast cancer, and a higher random effect of years was observed in 2010 and 2015.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.