In brief, the heterogeneity of patients changing from the 4/2 to the 2/1 schedule may be significant, so we believed that it was inappropriate if we included these patients as intervention or control groups.
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A 2/1 Sunitinib Dosing Schedule Provides Superior Antitumor Effectiveness and Less Toxicity Than a 4/2 Schedule for Metastatic Renal Cell Carcinoma: A Systematic Review and Meta-Analysis.
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