Nephroprotective effect of green tea, rosmarinic acid and rosemary on N-diethylnitrosamine initiated and ferric nitrilotriacetate promoted acute renal toxicity in Wistar rats.

Interdiscip Toxicol · 2019 · PMC7071836 · PMID 32206031

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highly significantp =0.000not a probability at all

The administration of Fe-NTA after DEN dose to albino rats resulted in acute nephrotoxicity which was characterized by a highly significant elevation of serum urea, creatinine, uric acid ( p =0.000), serum and renal MDA and TNF-α ( p =0.000) with vacuolation of epithelial lining renal tubules.

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