Conversely, in the transwell, LMNB1 expression was upregulated in HUVECs by U87MG, and Axitinib failed to significantly downregulate LMNB1 (although a decreasing trend was observed), likely because it does not suffice to blunt the upregulation induced by tumor cells per se, and irrespectively of senescence establishment.
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Glioblastoma Cells Do Not Affect Axitinib-Dependent Senescence of HUVECs in a Transwell Coculture Model.
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