Oxaloacetate reduces emotional symptoms in premenstrual syndrome (PMS): results of a placebo-controlled, cross-over clinical trial.

Compared with placebo (rather than baseline) depression, perceived stress and general anxiety were significantly improved with oxaloacetate/vitamin C treatment, with aggression trending toward significance ( P <0.05, P <0.05, P <0.05 and P =0.060, respectively).

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All results were highly significant.

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