The Genetic Basis of Natural Variation in <i>Drosophila melanogaster</i> Immune Defense against <i>Enterococcus faecalis</i>.

First, two highly significant ( p < 10 −9 ) SNPs were found in the intron of krishah ( kri ), and two additional SNPs with slightly lower significance ( p < 10 −7 ) were found in the 5′ untranslated region (UTR) of kri ( Figure S3 ). kri is tightly clustered with the genes S6k and mad2 ( Figure S3 ).

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There was a marginally significant trend for lower survival after infection in kri -flies ( n = 111 GOI and 177 control, Line effect p = 0.049, Table 1 , Figure 2 a).

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