Enhanced osteogenesis and therapy of osteoporosis using simvastatin loaded hybrid system.

Bioact Mater · 2020 · PMC7078127 · PMID 32206736

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an increasing trendno p-value reported

The OCN mRNA levels of the MHA-SIM-P group revealed more than the other two groups at day 7, and an increasing trend was demonstrated with a range of MHA-SIM-P > MHA > Blank at day 14 ( Fig. 2 e). 3.4 μCT analysis of femoral defect regeneration As shown in Fig. 3 a, the 3D μCT images of femur bone defect showed that the greatest amount of new bone formation was observed in the MHA-SIM-P group after surgery for 3 or 6 weeks.

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