Barely Significant
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CD28 and CD57 define four populations with distinct phenotypic properties within human CD8<sup>+</sup> T cells.

Eur J Immunol · 2020 · PMC7079235 · PMID 31755098

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a positive trendno p-value reported
Indeed, with age, a positive trend was found for DN CD8 + T cells in CMV + persons.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.