Role of early life immune regulation in asthma development.

Semin Immunopathol · 2020 · PMC7079989 · PMID 31873782

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highly significantno p-value reported

David Strachan published already in 1989 that there is a highly significant inverse link between hay fever and the number of older siblings [ 30 ], replicated in several studies.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.