Then, the relative expression of Ntn1 in the 10.5–14.5-day mouse embryos (time period that lip and palate fusion occurred) was detected in the proximal maxillary process with an increasing trend from E10.5d to E13.5d and then a decrease on E14.5d.
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The functional variant of NTN1 contributes to the risk of nonsyndromic cleft lip with or without cleft palate.
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