Zibotentan, an Endothelin A Receptor Antagonist, Prevents Amyloid-β-Induced Hypertension and Maintains Cerebral Perfusion.

J Alzheimers Dis · 2020 · PMC7081103 · PMID 31903990

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0630

boldest claim

The sentences

highly significantp < 0.0001actually significant

Comparison of best-fit regression lines by sum-of-squares F -test showed that the increases in MBP and SBP were highly significant ( p < 0.0001 for both) and the increase in DBP was also significant ( p = 0.0056).

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did not quite reach significancep = 0.063so close (0.05 < p ≤ 0.1)

For the second comparison, the mean RM EDN1 difference between Aβ and Aβ+zib groups was 630 pg/mL/mg tissue/mL buffer (–29.2–1288) which also did not quite reach significance ( p = 0.063; Fig. 2 b).

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