Relevance of reactive oxygen species in liver disease observed in transgenic mice expressing the hepatitis B virus X protein.

Lab Anim Res · 2020 · PMC7081669 · PMID 32206612

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The incidence of HCC (86%) in our HBx Tg mice may be highly significant, since the HBV X-gene Tg mice produced in other laboratories did not develop liver tumor or any other pathologic phenomena, except for one case [ 28 ].

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