Tumor mutation burden derived from small next generation sequencing targeted gene panel as an initial screening method.

Transl Lung Cancer Res · 2020 · PMC7082297 · PMID 32206555

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a decreasing trendno p-value reported

Meanwhile, the sensitivity also had a decreasing trend with the concomitant increase in the TMB in the validation cohort ( Table 4 ).

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an increasing trendno p-value reported

Both the specificity and PPV had an increasing trend with the increase in TMB achieving 100% when the TMB was at 21 mutations/Mb ( Figure S1 , Table 1 ).

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